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University of California
Stable Isotope Laboratory
Earth and Planetary Sciences
1156 High Street Santa Cruz, CA 95064

Lab: (831) 459-5751
Office: (831) 459-5857
Fax: (831) 459-3074

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Liquid Chromatographic (LC) Isotope Interface Principles


The Liquid Chromatographic (LC) Isolink interface is a device that oxidizes organic carbon with an oxidizing agent added to a solvent (typically water or an inorganic buffered solution). The solvent is also acidfied in order to drive sample carbonate species into aqueous carbon dioxide. This CO2(aq) rich solution is degassed through a CO2 permeable membrane and the CO2(g) is swept up in a helium carrier stream and is dried prior to introduction into the isotope ratio mass spectrometer.